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Identifiers
show IUPAC name
CAS Number	6740-88-1 33643-46-8 (esketamine) 33643-49-1 (arketamine) as HCl: 1867-66-9
PubChem CID TopChemSupply	3821
IUPHAR/BPS Top chem supply	4233
DrugBank	DB01221
ChemSpider	3689
UNII	690G0D6V8H
KEGG	D08098 as HCl: D00711
ChEBI	CHEBI:6121
ChEMBL	ChEMBL742
CompTox Dashboard (EPA)	DTXSID8023187
ECHA InfoCard	100.027.095
Chemical and physical data
Formula	C₁₃H₁₆ClNO
Molar mass	237.73 g·mol⁻¹
3D model (JSmol)	Interactive image
Chirality	Racemic mixture:^[13] Esketamine (S(+)-isomer) Arketamine (R(−)-isomer)
Melting point	92^[18] °C (198 °F)
SMILES
InChI

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SKU: N/A Categories: Hallucinogens, Pain

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Ketamine Hydrochloride is Systemic General Anesthetics. It is used as a sedative in diagnostic and surgical procedures, in which the patient does not need skeletal muscle relaxation. Buy Ketamine Hydrochloride. Ketalar is best suited for short procedures but when administered in additional doses, it can be used in longer procedures. Special K is used as anesthesia before general anesthetic agents are administered to supplement low-potency agents, such as nitrous oxide. While Ketamine Hydrochloride is a fast-acting anesthetic, it is also a hallucinogen and is more dangerous than other categories of hallucinogen drugs used for the same purpose. Buy Ketalar Online

Ketamine Hydrochloride is sold as Ketalar, bupivacaine amongst other brands. Parke Davis Laboratories was the first to synthesize Ketamine back in 1962. However, Ketamine’s history began in 1926, when it was developed as a derivative of PCP, as an anesthetic drug, that primarily acted as an NMDA receptor antagonist. Ketamine hydrochloride is a nonbarbiturate anesthetic. This synthetic derivative hydrochloride salt has analgesic and anesthetic properties. Buy Ketamine HCL. Top Chem Supply

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Special K for sale. While its mechanism of action is not clearly known, it seems to non-competitively block N-methyl-D-aspartate (NMDA) receptors and may interact with opioid mu receptors and sigma receptors. The overall result of this non-competitive binding is the reduction in pain perception, inducing sedation, and producing dissociative anesthesia. Buy Ketalar Online, Buy Ketamine HCL

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Buy Ketalar Online. N-methyl-D-aspartate (NMDA) systems, opioids receptors, dopamine receptors, cholinergic receptors, and wattage Ca signal transduction are some of the receptors that ketamine binds with. Ketamine does not interact with GABA receptors as other general anesthetics do. Ketamine is a fast-acting general anesthetic that causes severe analgesia, normal oesophageal reflexes, normal or slightly increased skeletal muscle tone, heart and circulatory acceleration, and, on rare occasions, temporary and minor respiratory depression.

Ketamine’s anesthetic state is known as dissociative anesthesia because it seems to selectively break brain association networks before generating somesthetic sensory blockade. It may depress the thalamocortical system selectively before obstructing the more primitive cerebral centers and connections (reticular-activating and limbic systems). Ketamine boosts descending inhibitory serotonin pathways, which can help with depression. These effects can be observed at doses ten times lower than what is required for anesthetic purposes. The analgesic action of ketamine is due to the suppression of central sensitization in nerve fibers cells as well as the reduction of nitric oxide production. Ketamine can cause bronchodilation and cardiovascular abnormalities. Buy Ketalar Online

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Ketamine Hydrochloride is available as a water-soluble crystalline powder for injection. The usual initial dose for adults is 1 to 4.5 mg per hour, administered through an IV slowly over 60 seconds. Generally, every 2 mg per kilo induces 5 to 10 minutes of surgical anesthesia. If a longer procedure, additional increments can be administered. The recommended dose for Adolescents aged 16 to 17 years is the same as above. Whereas the dose for Infants, Children, and Adolescents younger than 16 years is 0.5 to 2 mg per kilo. Buy Ketamine Hydrochloride

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Ketamine is a medication primarily used for induction and maintenance of anesthesia. It induces dissociative anesthesia, a trance-like state providing pain relief, sedation, and amnesia. The distinguishing features of ketamine anesthesia are preserved breathing and airway reflexes, stimulated heart function with increased blood pressure, and moderate bronchodilation. At lower, sub-anesthetic doses, ketamine is a promising agent for pain and treatment-resistant depression. However, the antidepressant action of a single administration of ketamine wanes with time and the effects of repeated use have not been sufficiently studied.